DEVELOPMENT OF L-ASPARAGINASE BIOBETTERS: CURRENT RESEARCH STATUS AND REVIEW OF THE DESIRABLE QUALITY PROFILES

Development of L-Asparaginase Biobetters: Current Research Status and Review of the Desirable Quality Profiles

L-Asparaginase (ASNase) is a vital component of the first line treatment of acute lymphoblastic leukemia (ALL), an aggressive type of blood cancer expected to afflict over 53,000 people worldwide by 2020.More recently, ASNase has also been shown to have potential for preventing metastasis from solid tumors.The ASNase treatment is, however, characte

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